Inhibitory Effects of Copaiba Essential Oil on the Inflammatory Response of RAW 264.7 Cells Treated with IFN-ɣ or LPS

Department

Biological Sciences

Advisor

Joy Doan

Document Type

Event

Version

Metadata Only

Abstract

Essential oils are compounds extracted from plants that are used to help reduce inflammation. Copaiba is an essential oil that is harvested from a tree in the Amazon. Copaiba has been used by native Amazonian tribes to treat inflammation and pathogenic diseases. Chronic inflammation can be connected to diseases such as cancer and cardiovascular disease (Campos-Cararo et al. 2023). Lipopolysaccharide (LPS) is a component of bacterial cell walls that is recognized by macrophages and induces the synthesis of pro-inflammatory cytokines (Huang and Kraus 2016). Interferon gamma (IFN-ɣ) is a proinflammatory cytokine that induces macrophage antimicrobial activity and NO production (Kopitar-Jerala 2017).

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May 11th, 1:30 PM

Inhibitory Effects of Copaiba Essential Oil on the Inflammatory Response of RAW 264.7 Cells Treated with IFN-ɣ or LPS

Essential oils are compounds extracted from plants that are used to help reduce inflammation. Copaiba is an essential oil that is harvested from a tree in the Amazon. Copaiba has been used by native Amazonian tribes to treat inflammation and pathogenic diseases. Chronic inflammation can be connected to diseases such as cancer and cardiovascular disease (Campos-Cararo et al. 2023). Lipopolysaccharide (LPS) is a component of bacterial cell walls that is recognized by macrophages and induces the synthesis of pro-inflammatory cytokines (Huang and Kraus 2016). Interferon gamma (IFN-ɣ) is a proinflammatory cytokine that induces macrophage antimicrobial activity and NO production (Kopitar-Jerala 2017).