Nano-Optical Tweezers: Methods and Applications for Trapping Single Molecules and Nanoparticles
Optical tweezers were developed in 1970 by Arthur Ashkin as a tool for the manipulation of micron-sized particles. Ashkin's original design was then adapted for a variety of purposes, such as trapping and manipulation of biological materials and the laser cooling of atoms.[2,3] More recent development has led to nano-optical tweezers, for trapping particles on the scale of only a few nanometers, and holographic tweezers, which allow for dynamic control of multiple traps in real-time. These alternatives to conventional optical tweezers have made it possible to trap single molecules and to perform a variety of studies on them. Presented here is a review of recent developments in nano-optical tweezers and their current and future applications.
Physics and Engineering
Kolbow, Joshua D.; Lindquist, Nathan C.; Ertsgaard, Christopher T.; Yoo, Daehan; and Oh, Sang Hyun, "Nano-Optical Tweezers: Methods and Applications for Trapping Single Molecules and Nanoparticles" (2021). Physics and Engineering Faculty Publications. 2.